Identification of benzopyran-4-one derivatives (isoflavones) as positive modulators of GABA(A) receptors

ChemMedChem. 2011 Aug 1;6(8):1340-6, 1317. doi: 10.1002/cmdc.201100120. Epub 2011 May 10.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Flumazenil / chemistry
  • Flumazenil / pharmacology
  • GABA Modulators / chemical synthesis
  • GABA Modulators / chemistry*
  • GABA Modulators / pharmacology
  • Humans
  • Isoflavones / chemical synthesis
  • Isoflavones / chemistry*
  • Isoflavones / pharmacology
  • Oocytes / drug effects
  • Oocytes / metabolism
  • Receptors, GABA-A / chemistry*
  • Receptors, GABA-A / genetics
  • Receptors, GABA-A / metabolism
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism
  • Structure-Activity Relationship
  • Xenopus

Substances

  • GABA Modulators
  • Isoflavones
  • Receptors, GABA-A
  • Recombinant Proteins
  • Flumazenil