Intrinsic DNA curvature of double-crossover tiles

Nanotechnology. 2011 Jun 17;22(24):245706. doi: 10.1088/0957-4484/22/24/245706. Epub 2011 May 4.

Abstract

A theoretical model which takes into account the structural distortion of double-crossover DNA tiles has been studied to investigate its effect on lattice formation sizes. It has been found that a single vector appropriately describes the curvature of the tiles, of which a higher magnitude hinders lattice growth. In conjunction with these calculations, normal mode analysis reveals that tiles with relative higher frequencies have an analogous effect. All the theoretical results are shown to be in good agreement with experimental data.

MeSH terms

  • Base Sequence
  • DNA / chemistry*
  • DNA / genetics
  • DNA / ultrastructure
  • Microscopy, Atomic Force
  • Molecular Sequence Data

Substances

  • DNA