Nanoparticles against Alzheimer's disease: PEG-PACA nanoparticles are able to link the aβ-peptide and influence its aggregation kinetic

J Control Release. 2010 Nov 20;148(1):e112-3. doi: 10.1016/j.jconrel.2010.07.084.

Authors

D Brambilla¹, R Verpillot, L De Kimpe, M Taverna, B Le Droumaguet, J Nicolas, M Canovi, M Gobbi, M Salmona, V Nicolas, W Scheper, P Couvreur, K Andrieux

Affiliation

¹ Laboratory of Physical-Chemistry, Pharmaceutical Technology and Biopharmacy, UMR CNRS 8612, University of Paris-Sud 11, Faculty of Pharmacy, 5 Rue J-B Clement, 92296 Chatenay-Malabry, France.

PMID: 21529583
DOI: 10.1016/j.jconrel.2010.07.084

No abstract available

MeSH terms

Alzheimer Disease / drug therapy*
Amyloid beta-Peptides / chemistry*
Cyanoacrylates / chemistry*
Cyanoacrylates / therapeutic use
Electrophoresis, Capillary
Humans
Kinetics
Nanoparticles / chemistry*
Nanoparticles / therapeutic use
Polyethylene Glycols / chemistry*
Polyethylene Glycols / therapeutic use

Substances

Amyloid beta-Peptides
Cyanoacrylates
polyethyleneglycol polyhexadecylylcyanoacrylate copolymer
Polyethylene Glycols