Anti-laminin-332 mucous membrane pemphigoid associated with recurrent metastatic prostate carcinoma: hypothesis for a paraneoplastic phenomenon

Eur J Dermatol. 2011 May-Jun;21(3):401-4. doi: 10.1684/ejd.2011.1360.

Abstract

Anti-epiligrin cicatricial pemphigoid is an autoimmune blistering disorder that has recently been associated with the development of solid organ malignancy. We describe a patient with recurrent metastatic prostate carcinoma who was diagnosed with this disorder. We provide a hypothesis as to the relationship between the development of this disease and its possible association with cancer pathogenesis.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Neoplasm / immunology*
  • Autoantibodies / immunology*
  • Cell Adhesion Molecules / immunology*
  • Cell Adhesion Molecules / metabolism
  • Humans
  • Kalinin
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / immunology*
  • Neoplasm Recurrence, Local / pathology
  • Paraneoplastic Syndromes / immunology*
  • Pemphigoid, Benign Mucous Membrane / immunology*
  • Pemphigoid, Benign Mucous Membrane / pathology
  • Prostate / immunology*
  • Prostate / pathology
  • Prostatic Neoplasms / complications
  • Prostatic Neoplasms / immunology

Substances

  • Antibodies, Neoplasm
  • Autoantibodies
  • Cell Adhesion Molecules