Serum lipid/lipoprotein and arterial blood pressure among Chinese nonagenarians/centenarians

Blood Press. 2011 Oct;20(5):296-302. doi: 10.3109/08037051.2011.572590.

Abstract

Objective: In the present study, we detected a relationship between serum lipid/lipoprotein [serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL)-cholesterol and high-density lipoprotein (HDL)-cholesterol] and arterial blood pressure among Chinese nonagenarians/centenarian.

Methods: The present study analyzed data from the survey that was conducted on all residents aged 90 years or more in a district; there were 2,311,709 inhabitants in 2005. Arterial blood pressure included systolic blood pressure (SBP) and diastolic blood pressure (DBP).

Results: The subjects included in the statistical analysis were 217 men and 444 women. Subjects with hypertension (1.29 ± 0.74 vs 1.13 ± 0.45, t = 3.362, p = 0.001) or systolic hypertension (1.30 ± 0.74 vs 1.12 ± 0.45, t = 3.534, p < 0.0001) had higher levels of TG than those without. Subjects with abnormal levels of serum TG had higher SBP (145 ± 22 vs 139 ± 23, t = 2.223, p = 0.027). The Pearson correlation showed a significant relationship between SBP and serum TG levels (r = 0.088, p = 0.024). Unadjusted and adjusted multiple logistic regressions showed that hypertension or systolic hypertension was associated with an increased risk of abnormal of serum TG levels.

Conclusions: In summary, we found that among Chinese nonagenarians and centenarians, the levels of serum lipid/lipoprotein were associated with arterial blood pressure. Hypertriglyceridemia was associated with SBP.

MeSH terms

  • Aged, 80 and over
  • Blood Pressure*
  • China / epidemiology
  • Cholesterol, HDL / blood*
  • Cholesterol, LDL / blood*
  • Cross-Sectional Studies
  • Diastole
  • Female
  • Humans
  • Hypertension* / blood
  • Hypertension* / epidemiology
  • Hypertension* / physiopathology
  • Logistic Models
  • Male
  • Systole
  • Triglycerides / blood*

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Triglycerides