Synthesis of chiral mesoporous silicas with oligo(saccharide) surfaces and their use in separation of stereoisomers

Edwin Vega; Cecilia Marzabadi; Yuri Kazakevich; Alexander Y Fadeev

doi:10.1016/j.jcis.2011.03.017

Synthesis of chiral mesoporous silicas with oligo(saccharide) surfaces and their use in separation of stereoisomers

J Colloid Interface Sci. 2011 Jul 15;359(2):542-4. doi: 10.1016/j.jcis.2011.03.017. Epub 2011 Mar 10.

Authors

Edwin Vega¹, Cecilia Marzabadi, Yuri Kazakevich, Alexander Y Fadeev

Affiliation

¹ Department of Chemistry and Biochemistry, Seton Hall University, South Orange, NJ 07079, USA.

PMID: 21514937
DOI: 10.1016/j.jcis.2011.03.017

Abstract

Novel chiral mesoporous silicas (SBA-15 motif) with chemically bonded oligo(saccharides) (1, 3, and 7 glucose units) were obtained through the cocondensation of organosilicon derivatives of the oligo(saccharides) and silica precursors in the presence of polymer surfactant template under mild acidic conditions. The pore order and structure of the materials prepared were characterized by transmission electron microscopy and nitrogen adsorption. The direct application of the oligo(saccharide)-grafted SBA-15 stationary phases in the HPLC separations of stereoisomers was demonstrated for the first time.