Synthesis and biological activity of N-acyl O-indolylalkyl ethanolamines

Biosci Biotechnol Biochem. 2011;75(4):768-70. doi: 10.1271/bbb.100804. Epub 2011 Apr 22.

Abstract

The plant-growth regulators, indole-3-carboxylic acids, were introduced into N-acyl ethanolamines, and a series of N-acyl O-indolylalkyl ethanolamines were prepared. Their biological activities to regulate rape hypocotyl elongation, cucumber cotyledon expansion and common wheat coleoptile growth were tested. The results indicate that the title compounds inhibited rape hypocotyl elongation, especially the indole-3-propionic acid derivatives, whose bioactivity was better than that of indole-3-acetic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ethanolamine / chemical synthesis*
  • Ethanolamine / chemistry
  • Ethanolamine / pharmacology*
  • Indoles / chemistry
  • Plant Development
  • Plant Growth Regulators / chemical synthesis*
  • Plant Growth Regulators / chemistry
  • Plant Growth Regulators / pharmacology*
  • Plants / drug effects
  • Structure-Activity Relationship

Substances

  • Indoles
  • Plant Growth Regulators
  • indole-3-carboxylic acid
  • Ethanolamine