Emergency evacuation! Hematopoietic niches induce cell exit in infection

Tatsuki Sugiyama; Takashi Nagasawa

doi:10.1016/j.immuni.2011.04.009

Emergency evacuation! Hematopoietic niches induce cell exit in infection

Immunity. 2011 Apr 22;34(4):463-5. doi: 10.1016/j.immuni.2011.04.009.

Authors

Tatsuki Sugiyama¹, Takashi Nagasawa

Affiliation

¹ Department of Immunobiology and Hematology, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

PMID: 21511181
DOI: 10.1016/j.immuni.2011.04.009

Abstract

The roles of hematopoietic stem and/or progenitor cell niches during infection remain unclear. In this issue of Immunity, Shi et al. (2011) reveal that these niches upregulate MCP1 chemokine expression, inducing emigration of bone marrow monocytes into the circulation via the endothelium.

Publication types

Comment