Two case reports of Clostridium difficile bacteremia, one with the epidemic NAP-1 strain

Infection. 2011 Aug;39(4):371-3. doi: 10.1007/s15010-011-0115-7. Epub 2011 Apr 21.

Abstract

Clostridium difficile bacteremia is rare. Here, we report two cases of C. difficile bacteremia in patients with significant underlying gastrointestinal pathology. In one case, the bacteremia was caused by the North American pulsed-field gel electrophoresis (PFGE) type 1 (NAP-1) strain, which is responsible for recent outbreaks of C. difficile infections of increased severity.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged, 80 and over
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / diagnosis
  • Bacteremia / drug therapy*
  • Bacteremia / epidemiology
  • Bacteremia / microbiology
  • Clostridioides difficile / classification*
  • Clostridioides difficile / drug effects
  • Clostridioides difficile / isolation & purification*
  • Clostridium Infections / diagnosis
  • Clostridium Infections / drug therapy*
  • Clostridium Infections / epidemiology
  • Clostridium Infections / microbiology
  • Comorbidity
  • Humans
  • Male
  • Ohio
  • Treatment Outcome
  • Vancomycin / therapeutic use
  • beta-Lactams / therapeutic use

Substances

  • Anti-Bacterial Agents
  • beta-Lactams
  • Vancomycin
  • Amikacin