Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases

Am J Obstet Gynecol. 2011 Jul;205(1):32.e1-4. doi: 10.1016/j.ajog.2011.02.044. Epub 2011 Feb 23.

Abstract

Objective: The objective of the study was to evaluate the clinical characteristics of ovarian teratoma by age.

Study design: This was a retrospective study. Five hundred eighty medical records were reviewed from patients who underwent operative removal of ovarian teratomas at Samsung Medical Center between January 1996 and February 2010.

Results: The proportion of asymptomatic patients increased significantly after 20 years of age (P = .0006). Ovarian torsion was noted in 26 patients (4.9%), without an age-specific difference (P = .5019; range, 0.0-8.2%). Tumor size was different according to age group (P < .0001), with larger tumor size in younger patients (<20 years old) relative to older patients. Immature teratoma revealed a higher incidence of symptomatic tumors on the first visit and significantly larger tumor size (P = .0004) compared with mature teratoma.

Conclusion: Patients with ovarian teratoma have different clinical manifestations by age. It could help us understand clinical characteristics of the disease.

MeSH terms

  • Abdominal Pain / epidemiology
  • Abdominal Pain / surgery
  • Adolescent
  • Adult
  • Age Factors
  • CA-125 Antigen / blood
  • CA-19-9 Antigen / blood
  • Child
  • Female
  • Humans
  • Incidence
  • Membrane Proteins / blood
  • Middle Aged
  • Ovarian Neoplasms / embryology
  • Ovarian Neoplasms / pathology*
  • Retrospective Studies
  • Teratoma / epidemiology
  • Teratoma / pathology*
  • Young Adult

Substances

  • CA-125 Antigen
  • CA-19-9 Antigen
  • MUC16 protein, human
  • Membrane Proteins