During the recent ten years operations were made on 331 patients with diffuse purulent peritonitis, 214 of them had traditional management of the postoperative period, 117 were managed using directed laparostomy by the method developed in the clinic. Toxic phase of peritonitis was noted in 66.76%, with the terminal phase--33.24% of patients, in the group of patients with laparostomy their number being 10% more than in the group of comparison (with a traditional method of management at the postoperative period). In cases with using directed laparostomy with programmed sanitation of the abdominal cavity the number of postoperative complications was 29.9%, 21.36% of patients died. In the group of patients with traditional management of the postoperative period there were 68.2% of complications, 80 patients (37.4) required relapatotomy, 55.6% died.