Potent inhibitors of 5-lipoxygenase identified using pseudoreceptors

ChemMedChem. 2011 Jun 6;6(6):1001-5. doi: 10.1002/cmdc.201100059. Epub 2011 Apr 19.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arachidonate 5-Lipoxygenase / metabolism*
  • Cell Line, Tumor
  • Drug Design*
  • Humans
  • L-Lactate Dehydrogenase / metabolism
  • Lipoxygenase Inhibitors / chemistry*
  • Lipoxygenase Inhibitors / pharmacology*
  • Models, Molecular
  • Neutrophils / drug effects
  • Neutrophils / enzymology

Substances

  • Lipoxygenase Inhibitors
  • L-Lactate Dehydrogenase
  • Arachidonate 5-Lipoxygenase