Impetigo herpetiformis with gestational hypertension: a case report and literature review

Dermatology. 2011;222(3):221-4. doi: 10.1159/000326913. Epub 2011 Apr 13.

Abstract

Background: Impetigo herpetiformis (IH) is a rare skin disorder that occurs during pregnancy. It was previously associated with high maternal and fetal mortality and morbidity, but now has a better prognosis.

Case report: We report a case of a pregnant woman with IH who presented with generalized erythematous pustular eruptions in the 32nd week of gestation. The IH progressed rapidly, and gestational hypertension was observed in the 36th week. The lesions did not subside, despite treatment with corticosteroids and phototherapy. She delivered a healthy male baby via cesarean section in the 37th week. One month after her delivery, her skin returned to normal, except for residual pigmentation, with complete recovery 3 months postpartum.

Conclusion: An experienced medical team comprising obstetricians, dermatologists, perinatologists and neonatologists is critical to aggressively treat this life-threatening specific dermatosis of pregnancy and to prevent ensuing complications, such as fluid and electrolyte imbalance, secondary infection and placental insufficiency.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Calcium / therapeutic use
  • Cesarean Section
  • Cyclosporine / therapeutic use
  • Dermatitis Herpetiformis / diagnosis
  • Dermatitis Herpetiformis / drug therapy
  • Dermatitis Herpetiformis / therapy
  • Dermatologic Agents / therapeutic use
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / diagnosis*
  • Hypertension, Pregnancy-Induced / drug therapy
  • Impetigo / complications
  • Impetigo / diagnosis*
  • Impetigo / drug therapy
  • Infant, Newborn
  • Live Birth
  • Male
  • Phototherapy
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / therapy
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Anti-Bacterial Agents
  • Dermatologic Agents
  • Cyclosporine
  • Calcium