Immunogenicity of a combined schedule of 7-valent pneumococcal conjugate vaccine followed by a 23-valent polysaccharide vaccine in adult recipients of heart or lung transplants

R Gattringer; H Winkler; S Roedler; P Jaksch; H Herkner; H Burgmann

doi:10.1111/j.1399-3062.2011.00628.x

Immunogenicity of a combined schedule of 7-valent pneumococcal conjugate vaccine followed by a 23-valent polysaccharide vaccine in adult recipients of heart or lung transplants

Transpl Infect Dis. 2011 Oct;13(5):540-4. doi: 10.1111/j.1399-3062.2011.00628.x. Epub 2011 Apr 13.

Authors

R Gattringer¹, H Winkler, S Roedler, P Jaksch, H Herkner, H Burgmann

Affiliation

¹ Department of Medicine I, Division of Infectious Diseases, Medical University of Vienna, Vienna, Austria.

PMID: 21489090
DOI: 10.1111/j.1399-3062.2011.00628.x

Abstract

A combined schedule of 7-valent pneumococcal conjugate vaccine (PCV7) followed by 23-valent pneumococcal polysaccharide vaccine (PPV23) was evaluated retrospectively in 26 adult recipients of heart or lung transplants. PCV7 was immunogenic in these patients but there appeared to be no benefit from the additional PPV23 dose.

Publication types

Clinical Trial

MeSH terms

Adult
Aged
Antibodies, Bacterial / blood
Antibodies, Bacterial / classification
Female
Heart Transplantation*
Humans
Immunoglobulin G / blood
Lung Transplantation*
Male
Middle Aged
Pneumococcal Infections / prevention & control*
Pneumococcal Vaccines / administration & dosage
Pneumococcal Vaccines / immunology*
Serotyping
Streptococcus pneumoniae / classification

Substances

Antibodies, Bacterial
Immunoglobulin G
Pneumococcal Vaccines