Abstract
Immune activation and inflammation can precipitate a variety of diseases. A screening assay for immunomodulatory properties is described. It is based on freshly isolated human peripheral blood mononuclear cells and allows testing for effects of nanoparticles on the human immune system.
MeSH terms
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Biological Assay / methods*
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Cells, Cultured
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Cytotoxicity Tests, Immunologic / methods*
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Humans
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Immunity, Innate / drug effects
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Immunity, Innate / immunology*
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Immunologic Factors / toxicity*
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Leukocytes, Mononuclear / drug effects
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Leukocytes, Mononuclear / immunology*
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Materials Testing / methods*
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Nanoparticles / toxicity*