Bilateral posterior ischemic optic neuropathy in a patient with severe diabetic ketoacidosis

Case Rep Ophthalmol. 2011 Feb 25;2(1):91-4. doi: 10.1159/000325141.

Abstract

Purpose: To report a case of bilateral posterior ischemic optic neuropathy (PION) in a patient with severe diabetic ketoacidosis (DKA).

Design: Observational case report.

Participant: A 35-year-old male who suffered bilateral visual loss during a severe episode of DKA.

Methods: Neuro-ophthalmological examination, neuroimaging consisting of a CT scan and MRI of the brain and orbits, as well as a MRA of brain vessels.

Results: Bilateral PION was diagnosed in a 35-year-old male with no light perception vision, who emerged from a coma caused by severe DKA. The patient developed optic nerve pallor in both eyes 4 weeks after the initial examination. Visual acuity with no light perception in both eyes remained unchanged after 6 months' follow-up.

Conclusions: Severe DKA can be complicated by bilateral PION, resulting in total blindness.

Keywords: Diabetes; Ketoacidosis; Neuropathy; Posterior ischemic optic neuropathy.

Publication types

  • Case Reports