[Proteomics and transfusion medicine]

Transfus Clin Biol. 2011 Apr;18(2):79-96. doi: 10.1016/j.tracli.2011.02.018. Epub 2011 Apr 5.
[Article in French]

Abstract

The term "proteomics" covers tools and techniques that are used to analyze and characterize complex mixtures of proteins from various biological samples. In this short review, a typical proteomic approach, related to the study of particular and illustrative situation related to transfusion medicine is reported. This "case report" will allow the reader to be familiar with a practical proteomic approach of a real situation, and will permit to describe the tools that are usually used in proteomic labs, and, in a second part, to present various proteomic applications in transfusion medicine.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Amino Acid Sequence
  • Blood Cells / chemistry
  • Blood Preservation
  • Blood Protein Electrophoresis / methods
  • Blood Proteins / analysis*
  • Blood Proteins / genetics
  • Blood Transfusion*
  • Cell-Derived Microparticles / chemistry
  • Chromatography / methods
  • Computational Biology
  • Flow Cytometry / methods
  • Humans
  • Mass Spectrometry / methods
  • Molecular Sequence Data
  • Platelet Membrane Glycoprotein IIb / blood
  • Platelet Membrane Glycoprotein IIb / chemistry
  • Proteomics* / methods
  • Specimen Handling / methods

Substances

  • Blood Proteins
  • Platelet Membrane Glycoprotein IIb