Abstract
Eleven patients with drug-resistant pandemic (H1N1) 2009 were identified in South Korea during May 2009-January 2010. Virus isolates from all patients had the H275Y mutation in the neuraminidase gene. One isolate had the I117M mutation. Of the 11 patients, 6 were ≥ 59 months of age, and 5 had underlying immunosuppressive conditions.
MeSH terms
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Adolescent
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Adult
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Antiviral Agents* / pharmacology
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Antiviral Agents* / therapeutic use
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Child
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Child, Preschool
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Drug Resistance, Viral / genetics*
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Female
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Humans
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Infant
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Influenza A Virus, H1N1 Subtype / drug effects*
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Influenza A Virus, H1N1 Subtype / genetics*
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Influenza, Human / complications
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Influenza, Human / drug therapy*
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Influenza, Human / mortality
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Male
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Middle Aged
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Mutation / genetics
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Oseltamivir* / pharmacology
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Oseltamivir* / therapeutic use
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Republic of Korea
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Treatment Outcome
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Viral Proteins / genetics
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Young Adult
Substances
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Antiviral Agents
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Viral Proteins
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Oseltamivir