Drug-resistant pandemic (H1N1) 2009, South Korea

Emerg Infect Dis. 2011 Apr;17(4):702-4. doi: 10.3201/eid1704.101467.

Abstract

Eleven patients with drug-resistant pandemic (H1N1) 2009 were identified in South Korea during May 2009-January 2010. Virus isolates from all patients had the H275Y mutation in the neuraminidase gene. One isolate had the I117M mutation. Of the 11 patients, 6 were ≥ 59 months of age, and 5 had underlying immunosuppressive conditions.

MeSH terms

  • Adolescent
  • Adult
  • Antiviral Agents* / pharmacology
  • Antiviral Agents* / therapeutic use
  • Child
  • Child, Preschool
  • Drug Resistance, Viral / genetics*
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H1N1 Subtype / drug effects*
  • Influenza A Virus, H1N1 Subtype / genetics*
  • Influenza, Human / complications
  • Influenza, Human / drug therapy*
  • Influenza, Human / mortality
  • Male
  • Middle Aged
  • Mutation / genetics
  • Oseltamivir* / pharmacology
  • Oseltamivir* / therapeutic use
  • Republic of Korea
  • Treatment Outcome
  • Viral Proteins / genetics
  • Young Adult

Substances

  • Antiviral Agents
  • Viral Proteins
  • Oseltamivir