Abstract
The total synthesis of atroviridin has been accomplished by a linear route involving the N-heterocyclic carbene (NHC)-catalyzed aroylation of the fluorobenzene derivative, Claisen cyclization of the O-propargylated benzophenones, and intramolecular 1,4-addition of the quinone intermediates. The result provides a viable route to xanthone natural products.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzoquinones / chemistry
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Biological Products / chemical synthesis*
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Biological Products / chemistry
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Catalysis
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Heterocyclic Compounds / chemistry*
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Methane / analogs & derivatives*
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Methane / chemistry
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Xanthones / chemical synthesis*
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Xanthones / chemistry
Substances
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Benzoquinones
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Biological Products
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Heterocyclic Compounds
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Xanthones
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atroviridin
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carbene
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quinone
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Methane