Abstract
A variety of chiral binaphthyl-based terminal-alkene-phosphine hybrid ligands were synthesized in four steps with (S)-BINOL as a starting material and utilized for the Pd-catalyzed enantioselective allylic alkylations of indoles and pyrroles to afford the desired products in high yields with good to excellent ee's.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Alkylation
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Catalysis
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Indoles / chemistry*
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Ligands
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Molecular Structure
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Palladium / chemistry*
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Phosphines / chemistry*
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Pyrroles / chemistry*
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Stereoisomerism
Substances
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Alkenes
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Indoles
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Ligands
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Phosphines
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Pyrroles
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Palladium
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phosphine