The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods

Bingnan Han; Uwe M Reinscheid; William H Gerwick; Harald Gross

doi:10.1016/j.molstruc.2011.01.012

The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods

J Mol Struct. 2011 Mar 15;989(1-3):109-113. doi: 10.1016/j.molstruc.2011.01.012.

Authors

Bingnan Han¹, Uwe M Reinscheid, William H Gerwick, Harald Gross

Affiliation

¹ Marine Resources Research Institute, Department of Ocean Science and Engineering, Xixi Campus, Zhejiang University, Hangzhou, China 310028.

Abstract

The 2Z-isomer of malyngamide K has been isolated along with the known compounds malyngamide C, deoxy-C and K, and characterized from a Papua New Guinea field collection of the cyanobacterium Lyngbya majuscula. The planar structure was deduced by 1D and 2D NMR spectroscopic and mass spectral data interpretation. The absolute configurations were determined on the basis of spectroscopic techniques, chemical degradation and DFT theoretical calculations.

Abstract

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