Studies on Pd/NiFe(2)O(4) catalyzed ligand-free Suzuki reaction in aqueous phase: synthesis of biaryls, terphenyls and polyaryls

Sanjay R Borhade; Suresh Babsaheb Waghmode

doi:10.3762/bjoc.7.41

Studies on Pd/NiFe(2)O(4) catalyzed ligand-free Suzuki reaction in aqueous phase: synthesis of biaryls, terphenyls and polyaryls

Beilstein J Org Chem. 2011 Mar 15:7:310-9. doi: 10.3762/bjoc.7.41.

Authors

Sanjay R Borhade¹, Suresh Babsaheb Waghmode

Affiliation

¹ Department of Chemistry, University of Pune, Ganeshkhind, Pune-411007, India.

Abstract

Palladium supported on nickel ferrite (Pd/NiF(2)O(4)) was found to be a highly active catalyst for the Suzuki coupling reaction between various aryl halides and arylboronic acids. The reaction gave excellent yields (70-98%) under ligand free conditions in a 1:1 DMF/H(2)O solvent mixture, in short reaction times (10-60 min). The catalyst could be recovered easily by applying an external magnetic field. The polyaryls were similarly synthesized.

Keywords: Suzuki reaction; heterogeneous catalysis; nickel ferrite; polyaryls; terphenyls.