High doses alprazolam induced amenorrhoea and galactorrhoea

Psychiatr Danub. 2011 Mar;23(1):123-4.

Abstract

Alprazolam belongs in the group of anxiolytics, medicaments used for reducing anxiety. As most other drugs, it can cause various adverse events, including hormonal disturbances and imbalance. Prolactin elevation is one such hormonal adverse event that can lead to galactorrhoea, or abnormal milk discharge from the breast and amenorrhoea. In this case report we will present the case of a female patient that developed galactorrhoea while treated with alprazolam, after all physical factors that can also cause these symptoms were excluded.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alprazolam / administration & dosage
  • Alprazolam / adverse effects*
  • Amenorrhea / chemically induced*
  • Anti-Anxiety Agents / administration & dosage
  • Anti-Anxiety Agents / adverse effects*
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / drug therapy*
  • Anxiety Disorders / psychology
  • Delayed-Action Preparations
  • Dose-Response Relationship, Drug
  • Female
  • Galactorrhea / chemically induced*
  • Humans
  • Self Medication
  • Somatoform Disorders / diagnosis
  • Somatoform Disorders / drug therapy
  • Somatoform Disorders / psychology

Substances

  • Anti-Anxiety Agents
  • Delayed-Action Preparations
  • Alprazolam