We report on the fabrication, fluorescence and laser properties of optical waveguides by swift nitrogen ion irradiation in Nd:YAG crystals. The confocal micro-luminescence investigations have concluded that the fluorescence features of the bulk material have been well preserved in the waveguide. Under 808 nm optical end-pumping, continuous-wave (cw) laser oscillation at 1064.2 nm has been demonstrated with laser slope efficiencies of 16% and pump power thresholds of 38.3 mW.