Craving, context and the cortex

Nat Neurosci. 2011 Apr;14(4):409-10. doi: 10.1038/nn.2787.

Abstract

A new study challenges the idea that the ventromedial prefrontal cortex inhibits drug relapse, by selectively inactivating a subpopulation of neurons in this brain area and showing attenuation of context-induced reinstatement of heroin seeking.

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Humans
  • Neural Pathways / drug effects
  • Neural Pathways / pathology
  • Neural Pathways / physiology*
  • Prefrontal Cortex / drug effects
  • Prefrontal Cortex / pathology
  • Prefrontal Cortex / physiology*
  • Rats
  • Reward*
  • Secondary Prevention
  • Substance-Related Disorders / pathology
  • Substance-Related Disorders / physiopathology
  • Substance-Related Disorders / psychology