Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients

Transplantation. 2011 Jan 15;91(1):e1-2. doi: 10.1097/TP.0b013e3181fa94a0.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
  • Case-Control Studies
  • Cell Proliferation / drug effects
  • Cytochrome P-450 CYP3A / genetics*
  • Everolimus
  • Haplotypes*
  • Humans
  • Hyperlipidemias / genetics
  • Hyperlipidemias / immunology
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation / adverse effects*
  • Proteinuria / genetics*
  • Proteinuria / immunology
  • Retrospective Studies
  • Signal Transduction
  • Sirolimus / adverse effects*
  • Sirolimus / analogs & derivatives*
  • Sirolimus / therapeutic use
  • Treatment Outcome

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Immunosuppressive Agents
  • Everolimus
  • CYP3A protein, human
  • Cytochrome P-450 CYP3A
  • Sirolimus