A case report: metastatic choriocarcinoma to the gum

Sex Reprod Healthc. 2011 Apr;2(2):91-2. doi: 10.1016/j.srhc.2011.02.001. Epub 2011 Feb 20.

Abstract

Choriocarcinoma is a rare neoplasia with a tendency of distant metastasis although highly sensitive to chemotherapy renders a good prognosis and outcome. Lungs, liver and cerebral metastasis are commonly implicated with maxillofacial region rarely involved. We illustrate a case of overwhelming metastatic choriocarcinoma to lungs, liver, brain and to the extreme of gum metastasis. Decompressive craniectomy for intracranial bleeding, multiple transfusions to correct anaemia and coagulopathy were done before high-risk-regime chemotherapy. Despite this, due to fulminant multi-organs involvement she finally succumbed to death. In conclusion, gum bleeding in choriocarcinoma may suggest metastasis and poor prognosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / secondary
  • Choriocarcinoma / drug therapy
  • Choriocarcinoma / pathology*
  • Fatal Outcome
  • Female
  • Gingival Neoplasms / complications
  • Gingival Neoplasms / drug therapy
  • Gingival Neoplasms / secondary*
  • Hemorrhage / etiology
  • Humans
  • Liver Neoplasms / secondary
  • Lung Neoplasms / secondary
  • Multiple Organ Failure
  • Pregnancy
  • Pregnancy Complications, Neoplastic / drug therapy*
  • Uterine Neoplasms / drug therapy
  • Uterine Neoplasms / pathology*
  • Young Adult