Use of controlled low dose gamma irradiation to sterilize allograft tendons for ACL reconstruction: biomechanical and clinical perspective

Brian J Samsell; Mark A Moore

doi:10.1007/s10561-011-9251-7

Use of controlled low dose gamma irradiation to sterilize allograft tendons for ACL reconstruction: biomechanical and clinical perspective

Cell Tissue Bank. 2012 Jun;13(2):217-23. doi: 10.1007/s10561-011-9251-7. Epub 2011 Mar 23.

Authors

Brian J Samsell¹, Mark A Moore

Affiliation

¹ LifeNet Health, 1864 Concert Drive, Virginia Beach, VA 23453, USA.

Abstract

As reviewed here, numerous biomechanical and clinical studies support the use of controlled, low temperature irradiation of allograft tendons, to provide both excellent clinical results and medical-device grade sterile allografts with minimal risk of disease transmission.

Publication types

Review

MeSH terms

Animals
Anterior Cruciate Ligament / surgery*
Biomechanical Phenomena / radiation effects
Dose-Response Relationship, Radiation
Gamma Rays*
Humans
Plastic Surgery Procedures / methods*
Sterilization / methods*
Tendons / radiation effects*
Tendons / transplantation*
Transplantation, Homologous