Exogenous enzymes are now well accepted as a class of feed additives in diet formulations for poultry and pigs to overcome the negative effects of anti-nutritional factors, and to improve digestion of dietary components and animal performance. An overview of the current status of feed enzyme technology, including the different type of enzymes and modes of action, is provided. Variable response to enzyme supplementation is an important reason limiting the widespread acceptance of feed enzymes. The major reasons contributing to these variable responses are discussed. Main features of the next generation of feed enzymes and the various trends that will drive the future use of enzymes are highlighted. The use of feed enzymes in poultry and pig feed formulations is expected to increase in the future and this will be driven by on-going changes in the world animal production. Aquaculture and ruminant industries are emerging markets for exogenous feed enzymes. The article presents some promising patents on feed enzyme technology.