Ankylosing spondylitis presented as unilateral optic neuritis in a young woman

Ocul Immunol Inflamm. 2011 Apr;19(2):115-7. doi: 10.3109/09273948.2010.530732.

Abstract

Purpose: To report a case of ankylosing spondylitis that initially presented as unilateral optic neuritis.

Methods: Case report.

Design: Clinical findings and treatment are presented. A 31-year-old woman presented with unilateral optic neuritis in her right eye. Her symptom improved following pulse steroid therapy. Unfortunately, she developed severe pain and weakness in her bilateral knee and ankle joints during follow-up. Further investigation revealed a positive finding of HLA-B27 and bilateral sacroiliitis. Ankylosing spondylitis was confirmed and was treated with Salazine and Mobic.

Conclusions: Optic neuritis is rarely the first symptom of AS. Careful surveying and prompt treatment is necessary.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Arthralgia / chemically induced
  • Color Vision
  • Drug Therapy, Combination
  • Female
  • Fundus Oculi
  • HLA-B27 Antigen / blood
  • Humans
  • Meloxicam
  • Optic Neuritis / drug therapy
  • Optic Neuritis / etiology*
  • Optic Neuritis / pathology
  • Optic Neuritis / physiopathology
  • Pulse Therapy, Drug
  • Radionuclide Imaging
  • Sacroiliitis / diagnostic imaging
  • Sacroiliitis / genetics
  • Spondylitis, Ankylosing / complications*
  • Spondylitis, Ankylosing / drug therapy
  • Spondylitis, Ankylosing / immunology
  • Steroids / administration & dosage
  • Steroids / adverse effects
  • Sulfasalazine / therapeutic use
  • Thiazines / therapeutic use
  • Thiazoles / therapeutic use
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • HLA-B27 Antigen
  • Steroids
  • Thiazines
  • Thiazoles
  • Sulfasalazine
  • Meloxicam