Role of tetrahydrobiopterin (BH4) in hyperhomocysteinemia-induced endothelial dysfuction: new indication for this orphan-drug?

Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1176; author reply E1177-8. doi: 10.1152/ajpendo.00084.2011. Epub 2011 Mar 22.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Biopterins / analogs & derivatives*
  • Biopterins / analysis
  • Biopterins / metabolism
  • Biopterins / physiology
  • Coronary Circulation / physiology
  • Coronary Disease / etiology
  • Coronary Disease / pathology
  • Coronary Vessels / diagnostic imaging
  • Endothelium, Vascular / pathology*
  • Humans
  • Hyperhomocysteinemia / complications*
  • Hyperhomocysteinemia / diagnostic imaging
  • Hyperhomocysteinemia / metabolism*
  • Nitric Oxide / blood
  • Orphan Drug Production*
  • Oxidation-Reduction
  • Ultrasonography
  • Vascular Diseases / pathology*

Substances

  • Biopterins
  • Nitric Oxide
  • sapropterin