[What's new in the treatment of seminomas?]

Cancer Radiother. 2011 Jun;15(3):208-20. doi: 10.1016/j.canrad.2010.09.004. Epub 2011 Mar 17.
[Article in French]

Abstract

Pure testicular seminoma is a rare disease with an excellent prognosis. Its management is controversial. In stage I disease, several treatment options are considered. Those are radiation therapy alone, chemotherapy alone or active surveillance, which is becoming increasingly popular. For more advanced stages, treatment is based on chemotherapy with or without radiation therapy. In this article, we review thoroughly the existing literature and recent recommendations the various treatment options, their advantages and disadvantages in different stages of the disease.

Publication types

  • Review

MeSH terms

  • Adult
  • Antineoplastic Agents, Alkylating / administration & dosage
  • Antineoplastic Agents, Alkylating / therapeutic use
  • Chorionic Gonadotropin, beta Subunit, Human / metabolism
  • Combined Modality Therapy
  • Disease Management
  • Humans
  • Lymphatic Irradiation
  • Male
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Second Primary / etiology
  • Orchiectomy
  • Organoplatinum Compounds / administration & dosage
  • Organoplatinum Compounds / therapeutic use
  • Practice Guidelines as Topic
  • Prognosis
  • Radiation Tolerance
  • Radiotherapy / adverse effects
  • Radiotherapy / methods
  • Retrospective Studies
  • Risk Factors
  • Seminoma / epidemiology
  • Seminoma / metabolism
  • Seminoma / pathology
  • Seminoma / secondary
  • Seminoma / therapy*
  • Testicular Neoplasms / epidemiology
  • Testicular Neoplasms / metabolism
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / therapy*
  • Therapies, Investigational
  • Young Adult

Substances

  • Antineoplastic Agents, Alkylating
  • Chorionic Gonadotropin, beta Subunit, Human
  • Organoplatinum Compounds