[Myopia and retinal striae induced by topiramate]

Arch Soc Esp Oftalmol. 2011 Jan;86(1):24-6. doi: 10.1016/j.oftal.2010.10.009. Epub 2011 Feb 19.
[Article in Spanish]

Abstract

Clinical case: A 23-year-old woman who was seen due to decreasing far visual acuity 24hours after starting treatment with topiramate. In the cycloplegic refraction, RE showed -4.25 and LE -4.50. Retinal striae could be seen in the macula of both eyes. The alterations ceased 48hours after the drug treatment was interrupted.

Discussion: Drug induced acute myopia is an infrequent phenomenon, the aetiology of which is still not fully known.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use
  • Female
  • Fructose / adverse effects
  • Fructose / analogs & derivatives*
  • Fructose / therapeutic use
  • Humans
  • Macula Lutea / drug effects
  • Macula Lutea / pathology
  • Migraine Disorders / prevention & control
  • Mydriatics / pharmacology
  • Myopia / chemically induced*
  • Retinal Diseases / chemically induced*
  • Topiramate
  • Young Adult

Substances

  • Anticonvulsants
  • Mydriatics
  • Topiramate
  • Fructose