This research aimed to study children's psychopathology and unintentional accidents in Thrace, northern Greece. We examined whether there was a correlation between each risk factor of the research and the dependent variables: 1) minor accidents, 2) serious accidents that required Emergency Room attendance (ER accidents), 3) serious accidents that led to hospital admission (admission accidents). High school children (n = 1,516) completed an anonymous questionnaire regarding the cause of their accident, as well as the "Strengths and difficulties questionnaire" (SDQ) by Goodman. The results indicate that sex, conduct disorders, hyperactivity, and abnormal score in SDQ were important risk factors for minor injuries and continued to be important risk factors for ER accidents. Sex, conduct disorders, hyperactivity, peer-problems, and abnormal score in SDQ were important risk factors for the most serious accidents (admission accidents). Because major accidents can result in serious health problems or disability, attention should be paid to the risk factors found.