"Fuzzy oil drop" model verified positively

Bioinformation. 2011 Feb 7;5(9):375-7. doi: 10.6026/97320630005375.

Abstract

The "fuzzy oil drop" model assuming the structure of the hydrophobic core of the form of 3-D Gauss function appeared to be verified positively. The protein 1NMF belonging to downhill proteins was found to represent the hydrophobic density distribution accordant with the assumed model. The accordance of the protein structure with the assumed model was measured using elements of theory information. This observation opens the possibility to simulate the folding process as influenced by external force field of hydrophobic character.

Keywords: downhill proteins; hydrophobic core.