Integration of biomolecules and nanomaterials: towards highly selective and sensitive biosensors

Biotechnol J. 2011 Nov;6(11):1310-6. doi: 10.1002/biot.201100006. Epub 2011 Mar 7.

Abstract

Significant efforts have been made toward the development of high-performance biosensors for various applications. Advances in nanotechnology have resulted in the development of highly sensitive electrochemical sensing devices. It is believed that highly sensitive and selective biosensors can be realized through the integration of biomolecules and nanomaterial-based sensor platforms. Numerous articles have described combining biomolecules as recognition elements with nanotechnology for the development of biosensors with enhanced selectivity and sensitivity. Recent advances in the development of biosensors through the integration of biomolecules with nanotechnology are reviewed in this article.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biosensing Techniques / instrumentation*
  • Glucose Oxidase / metabolism
  • Nanotechnology / methods*
  • Nanotechnology / trends
  • Nanotubes, Carbon / chemistry*
  • Receptors, Odorant / metabolism
  • Sequence Analysis, DNA / methods

Substances

  • Nanotubes, Carbon
  • Receptors, Odorant
  • Glucose Oxidase