A new diterpenoid glucoside and two new diterpenoids from the fruit of Vitex agnus-castus

Chem Pharm Bull (Tokyo). 2011;59(3):392-6. doi: 10.1248/cpb.59.392.

Abstract

A new labdane-type diterpenoid glucoside and two new labdane-type diterpenoids were isolated from the fruit (chasteberry) of Vitex agnus-castus L. (Verbenaceae) along with 14 known compounds comprising seven labdane-type diterpenoids, one halimane-type diterpenoid, two oleanane-type triterpenoids, two ursane-type triterpenoids, one aromadendrane-type sesquiterpenoid, and one flavonoid. Their structures were characterized on the basis of spectroscopic data as well as chemical evidence. Furthermore, the antioxidative activities of the flavonoid were evaluated using five different analyses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Diterpenes / chemistry*
  • Diterpenes / isolation & purification
  • Diterpenes / pharmacology
  • Fruit / chemistry
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Glucosides / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Vitex / chemistry*

Substances

  • (3S,5S,8R,9R,10S)-3,9-dihydroxy-13(14)-labdaen-16,15- olide 3-O-beta-D-glucopyranoside
  • (rel 5S,6R,8R,9R,10S,13S,16R)-6-acetoxy-9,13-epoxy-16- methoxy-labdan-15,16-olide
  • Antioxidants
  • Diterpenes
  • Glucosides
  • viteagnuside J