Abstract
Summary of and comment on a recent Cell paper entitled ‘Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival’ (Zhou et al., 2010).
MeSH terms
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Activin Receptors, Type II / metabolism
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Activins / metabolism*
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Animals
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Cachexia / complications*
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Cachexia / metabolism*
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Disease Models, Animal
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Humans
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Mice
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Muscle, Skeletal / metabolism
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Muscle, Skeletal / pathology
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Neoplasms / complications*
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Neoplasms / metabolism*
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Signal Transduction
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Transforming Growth Factor beta / metabolism
Substances
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Transforming Growth Factor beta
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Activins
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Activin Receptors, Type II
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activin receptor type II-B