Cholinergic urticaria: pathogenesis-based categorization and its treatment options

J Eur Acad Dermatol Venereol. 2012 Jan;26(1):114-6. doi: 10.1111/j.1468-3083.2011.04017.x. Epub 2011 Mar 4.

Abstract

Background: Cholinergic urticaria (CU) has well-described characteristic clinical presentations, yet the precise pathological mechanism remains incompletely understood. A variety of pathogeneses has been proposed, which suggests that there exists several clinical subtypes.

Conclusions: In this review, we categorize CU into four subtypes: (i) CU with poral occlusion; (ii) CU with acquired generalized hypohidrosis; (iii) CU with sweat allergy; and (iv) idiopathic CU, and discuss diagnostic and treatment options.

Publication types

  • Review

MeSH terms

  • Humans
  • Receptors, Cholinergic / physiology*
  • Urticaria / classification
  • Urticaria / etiology*
  • Urticaria / physiopathology
  • Urticaria / therapy

Substances

  • Receptors, Cholinergic