Water soluble heptakis(6-deoxy-6-thio)cyclomaltoheptaose capped gold nanoparticles via metal vapour synthesis: NMR structural characterization and complexation properties

Gloria Uccello-Barretta; Claudio Evangelisti; Federica Balzano; Letizia Vanni; Federica Aiello; Laszlo Jicsinszky

doi:10.1016/j.carres.2011.02.001

Water soluble heptakis(6-deoxy-6-thio)cyclomaltoheptaose capped gold nanoparticles via metal vapour synthesis: NMR structural characterization and complexation properties

Carbohydr Res. 2011 May 1;346(6):753-8. doi: 10.1016/j.carres.2011.02.001. Epub 2011 Feb 28.

Authors

Gloria Uccello-Barretta¹, Claudio Evangelisti, Federica Balzano, Letizia Vanni, Federica Aiello, Laszlo Jicsinszky

Affiliation

¹ Dipartimento di Chimica e Chimica Industriale, Università degli Studi di Pisa, via Risorgimento 35, I-56126 Pisa, Italy. gub@dcci.unipi.it

PMID: 21367401
DOI: 10.1016/j.carres.2011.02.001

Abstract

The complexation of heptakis(6-deoxy-6-thio)cyclomaltoheptaose to gold nanoparticles prepared by using the Metal Vapour Synthesis (MVS) led to water soluble gold nanoaggregates, thermally stable at 25°C. The role of gold concentration in the MVS-derived starting solution as well as of the cyclodextrin to gold molar ratio on the size of cyclodextrin-capped gold nanoparticles were investigated. The ability of cyclodextrin bonded to gold nanoparticles to include deoxycytidine was also probed in comparison with that of 1-thio-β-D-glucose sodium salt.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gold / chemistry*
Magnetic Resonance Spectroscopy
Metal Nanoparticles / chemistry*
Molecular Structure
beta-Cyclodextrins / chemistry*

Substances

beta-Cyclodextrins
Gold
betadex