Clinical features and outcome of children and adolescents hospitalized with influenza A (H1N1) virus infection compared with flu-like symptoms and negative rapid tests for influenza A (H1N1) admitted in the same period of time

J Trop Pediatr. 2011 Dec;57(6):481-3. doi: 10.1093/tropej/fmr023. Epub 2011 Feb 25.

Abstract

This report describes the clinical features and outcome of 61 pediatric hospitalized patients with influenza-like infection. Fever, cough and respiratory distress were the most common symptoms of the infection. Fifteen patients presented positive RT-PCR results for influenza A (H1N1). The group with positive results was compared with the negative one. The main significant difference was antibiotic usage and the need of mechanical ventilation in the patients with H1N1-virus infection. Among the 11 patients who required intensive care due to respiratory failure, 3 from the positive group died and none from the negative group.

Publication types

  • Comparative Study

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Child
  • Child, Preschool
  • Critical Care
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human* / diagnosis
  • Influenza, Human* / mortality
  • Influenza, Human* / therapy
  • Length of Stay
  • Male
  • Oseltamivir / therapeutic use
  • Respiration, Artificial
  • Respiratory Tract Infections / diagnosis
  • Respiratory Tract Infections / mortality
  • Respiratory Tract Infections / therapy
  • Reverse Transcriptase Polymerase Chain Reaction
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Antiviral Agents
  • Oseltamivir