MPID-T2: a database for sequence-structure-function analyses of pMHC and TR/pMHC structures

Javed Mohammed Khan; Harish Reddy Cheruku; Joo Chuan Tong; Shoba Ranganathan

doi:10.1093/bioinformatics/btr104

MPID-T2: a database for sequence-structure-function analyses of pMHC and TR/pMHC structures

Bioinformatics. 2011 Apr 15;27(8):1192-3. doi: 10.1093/bioinformatics/btr104. Epub 2011 Feb 23.

Authors

Javed Mohammed Khan¹, Harish Reddy Cheruku, Joo Chuan Tong, Shoba Ranganathan

Affiliation

¹ Department of Chemistry and Biomolecular Sciences and ARC Centre of Excellence in Bioinformatics, Macquarie University, Sydney, NSW, Australia.

PMID: 21349870
DOI: 10.1093/bioinformatics/btr104

Abstract

Sequence-structure-function information is critical in understanding the mechanism of pMHC and TR/pMHC binding and recognition. A database for sequence-structure-function information on pMHC and TR/pMHC interactions, MHC-Peptide Interaction Database-TR version 2 (MPID-T2), is now available augmented with the latest PDB and IMGT/3Dstructure-DB data, advanced features and new parameters for the analysis of pMHC and TR/pMHC structures.

Availability: http://biolinfo.org/mpid-t2.

Contact: shoba.ranganathan@mq.edu.au

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

Animals
Databases, Protein*
Histocompatibility Antigens Class I / chemistry*
Histocompatibility Antigens Class II / chemistry*
Humans
Peptides / chemistry
Protein Binding
Receptors, Antigen, T-Cell / chemistry*
Sequence Analysis, Protein
Structure-Activity Relationship

Substances

Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Peptides
Receptors, Antigen, T-Cell