Role of Helicobacter species in Chinese patients with inflammatory bowel disease

J Clin Microbiol. 2011 May;49(5):1987-9. doi: 10.1128/JCM.02630-10. Epub 2011 Feb 23.

Abstract

Based on 16S rRNA gene PCR, no significant difference was observed in rates of detection of Helicobacter species in intestinal biopsy specimens from 160 Chinese inflammatory bowel disease (IBD) patients (10%) and 80 controls (6.3%). By using a [(13)C]urea breath test, the H. pylori infection rate in 208 Chinese IBD patients (19.7%) was found to be significantly lower than that in 416 controls (48.8%).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Asian People
  • Breath Tests
  • Carbon Isotopes / metabolism
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Female
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / epidemiology*
  • Helicobacter Infections / microbiology
  • Helicobacter pylori / genetics
  • Helicobacter pylori / isolation & purification
  • Helicobacter pylori / pathogenicity*
  • Humans
  • Inflammatory Bowel Diseases / complications*
  • Inflammatory Bowel Diseases / microbiology
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • RNA, Ribosomal, 16S / genetics
  • Urea / metabolism

Substances

  • Carbon Isotopes
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S
  • Urea