The impact on health of work carried out within the household is recognized by several authors in the occupational health field. The purpose of this article is to verify whether and to what extent the need for recovery is related to professional work hours and to housework duties in female nursing workers. Workers (N = 1122) completed a questionnaire with data on household chores and professional work, as well as the Need for Recovery from Work scale. Regression analysis showed that the odds for reporting poor recovery were significantly higher for workers showing long domestic work hours, high total work load (professional plus domestic work hours), and housework overload. No association was found for professional work hours per se. Findings highlight the potential detrimental effects of housework, either by itself or in combination with professional work for the group studied, and can generate discussion on gender equality in both the public and private domains.