Structure elucidation and complete NMR spectral assignment of an unusual aromatic monacolin analog from Monascus purpureus-fermented rice

Magn Reson Chem. 2011 Mar;49(3):129-31. doi: 10.1002/mrc.2714. Epub 2011 Jan 18.

Abstract

One unusual aromatic monacolin analog, monacophenyl, was isolated from the ethanolic extract of Monascus purpureus-fermented rice. Its structure was completely and unambiguously assigned by one- and two-dimensional NMR techniques ((1)H NMR, (13)C NMR, HSQC, HMBC and NOESY) and high-resolution ESI-MS spectrometry.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anticholesteremic Agents / chemistry
  • Lovastatin / analogs & derivatives
  • Lovastatin / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Monascus / chemistry*
  • Oryza / chemistry*
  • Pyrones / chemistry*
  • Tetrahydronaphthalenes / chemistry*

Substances

  • Anticholesteremic Agents
  • Pyrones
  • Tetrahydronaphthalenes
  • Lovastatin