Herd immunity after two years of the universal mass vaccination program against rotavirus gastroenteritis in Austria

Vaccine. 2011 Mar 24;29(15):2791-6. doi: 10.1016/j.vaccine.2011.01.104. Epub 2011 Feb 12.

Abstract

Austria was the first country in Europe implementing a universal mass vaccination program against rotavirus gastroenteritis (RV-GE) for all infants nationwide. Epidemiological data from a hospital based surveillance system show that incidence rates of children hospitalized with RV-GE decreased in 2009 compared to 2008 and compared to the prevaccination period 2001-2005. Decreasing hospitalization-rates from RV-GE were observed in children of all age groups, even in those not eligible for vaccination according to their age, suggesting herd immunity induced by universal mass vaccination against RV-GE. In 2009 the disease burden was highest in children below three months of age stressing the importance of the early start of the immunization course.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Austria / epidemiology
  • Child
  • Child, Preschool
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / immunology
  • Gastroenteritis / prevention & control
  • Hospitalization / statistics & numerical data
  • Humans
  • Immunity, Herd*
  • Incidence
  • Infant
  • Infant, Newborn
  • Mass Vaccination*
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / immunology
  • Rotavirus Infections / prevention & control
  • Rotavirus Vaccines / administration & dosage
  • Rotavirus Vaccines / immunology*

Substances

  • Rotavirus Vaccines