The emerging use of technology for the treatment of depression and other neuropsychiatric disorders

Ann Clin Psychiatry. 2011 Feb;23(1):48-62.

Abstract

Background: Our objective is to review emerging technologies intended for the treatment of depression and other neuropsychiatric disorders.

Methods: These technologies include repetitive transcranial magnetic stimulation (rTMS), magnetic seizure therapy (MST), vagus nerve stimulation (VNS), deep brain stimulation (DBS), cortical brain stimulation (CBS), and quantitative electroencephalography (QEEG).

Results: The rationale for these technologies, their mechanisms of action, and how they are used in clinical practice are described. rTMS and VNS are effective for treatment-resistant depression. DBS is effective for resistant obsessive-compulsive disorder. QEEG can help predict a patient's response to an antidepressant. All of these technologies continue to be investigated in treatment studies.

Conclusions: As these and other emerging technologies for depression and other neuropsychiatric disorders are development and applied, psychiatrists should understand the rationale for these modalities, how they work, and how they can be used in clinical practice.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / pharmacology
  • Cerebral Cortex / metabolism
  • Cerebral Cortex / physiopathology
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Depressive Disorder* / metabolism
  • Depressive Disorder* / physiopathology
  • Depressive Disorder* / psychology
  • Depressive Disorder* / therapy
  • Drug Resistance
  • Electroconvulsive Therapy / adverse effects
  • Electroconvulsive Therapy / methods*
  • Electroencephalography / adverse effects
  • Electroencephalography / methods*
  • Humans
  • Neuropsychology / methods
  • Obsessive-Compulsive Disorder* / metabolism
  • Obsessive-Compulsive Disorder* / physiopathology
  • Obsessive-Compulsive Disorder* / psychology
  • Obsessive-Compulsive Disorder* / therapy
  • Therapies, Investigational
  • Transcranial Magnetic Stimulation / adverse effects
  • Transcranial Magnetic Stimulation / methods*
  • Treatment Outcome
  • Vagus Nerve Stimulation / adverse effects
  • Vagus Nerve Stimulation / methods*

Substances

  • Antidepressive Agents