[Synthesis and antiviral evaluation against Vaccinia virus of new N¹-oxide analogues of 5'-noraristeromycin]

E S Matiugina; K L Seley-Radtke; V L Andronova; G A Galegov; S N Kochetkov; A L Khandazhinskaia

[Synthesis and antiviral evaluation against Vaccinia virus of new N¹-oxide analogues of 5'-noraristeromycin]

Bioorg Khim. 2010 Nov-Dec;36(6):797-801.

[Article in Russian]

Authors

E S Matiugina, K L Seley-Radtke, V L Andronova, G A Galegov, S N Kochetkov, A L Khandazhinskaia

PMID: 21317946

Abstract

New N¹-benzyl esters of N¹-oxide analogues of 5'-noraristeromycin were synthesized and tested as potential inhibitors of S-adenosyl-L-homocysteine hydrolase in Vaccinia virus infected cell systems.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenosine / analogs & derivatives*
Adenosine / chemical synthesis
Adenosine / chemistry
Adenosine / pharmacology
Animals
Antiviral Agents / chemical synthesis*
Antiviral Agents / chemistry
Antiviral Agents / pharmacology*
Chlorocebus aethiops
Drug Evaluation, Preclinical
Humans
Vaccinia / drug therapy*
Vaccinia virus*
Vero Cells

Substances

Antiviral Agents
5'-noraristeromycin
Adenosine