The role of endoscopic ultrasound in the evaluation of chronic mesenteric ischaemia

Dig Liver Dis. 2011 Jun;43(6):470-4. doi: 10.1016/j.dld.2011.01.003. Epub 2011 Feb 11.

Abstract

Introduction: Doppler transabdominal ultrasound is a validated screening test for chronic mesenteric ischaemia, but gas and obesity are limitations. Endoscopic ultrasound has been proposed as a comprehensive test to evaluate chronic upper abdominal pain and is capable of Doppler measurement. We aim to evaluate the accuracy of Doppler endoscopic ultrasound (D-EUS) as a single screening test to rule out chronic mesenteric ischaemia in patients with abdominal pain and compare it with Doppler transabdominal ultrasound (D-TUS).

Methods: We enrolled all patients ≥50 years with chronic upper abdominal pain and vascular risk referred for endoscopic ultrasound. All were scheduled for D-EUS and D-TUS plus a confirmatory test if one of the previous resulted positive. We estimated the accuracy of both techniques comparing them using McNemar test.

Results: 68 patients completed the study. Fifty-three (78%) underwent D-EUS, D-TUS, and a confirmatory test. Fifteen (38%) underwent follow-up after negative results. Three (4%) in the D-EUS group and 14 in the D-TUS (21%) were excluded due to artefacts. D-EUS presented a sensitivity of 63%, specificity of 84%, whilst D-TUS presented a sensitivity of 80% and a specificity of 78%. Specificity of D-EUS was not significantly different to D-TUS.

Conclusions: These results support the role of Doppler endoscopic ultrasound to exclude chronic mesenteric ischaemia as cause of chronic abdominal pain.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Pain / diagnostic imaging
  • Abdominal Pain / etiology*
  • Aged
  • Aged, 80 and over
  • Chronic Disease
  • Diagnosis, Differential
  • Endosonography / methods*
  • Female
  • Humans
  • Ischemia / complications
  • Ischemia / diagnostic imaging*
  • Male
  • Mesenteric Arteries / diagnostic imaging
  • Mesenteric Arteries / pathology
  • Mesenteric Vascular Occlusion / complications
  • Mesenteric Vascular Occlusion / diagnostic imaging*
  • Middle Aged
  • Pilot Projects
  • Prospective Studies
  • Sensitivity and Specificity
  • Ultrasonography, Doppler