Organelle-selective energy transfer: a fluorescent indicator of intracellular environment

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1849-51. doi: 10.1016/j.bmcl.2011.01.040. Epub 2011 Jan 15.

Abstract

A dye cassette fluoresces green (ca 520 nm) in the cytoplasm, endoplasmic reticulum (ER), and lysosomes, but red in mitochondria, that is, it illustrates 'organelle specific energy transfer'. This phenomenon may open new horizons in intracellular imaging.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescent Dyes / metabolism*
  • Microscopy, Fluorescence
  • Organelles / metabolism*

Substances

  • Fluorescent Dyes